Abstract

Case Report

Acyclovir Induced Acute Kidney Injury: A Case Report

Ziauddin Mohammed*, Mariya Zoha Muskan and Megha Mohan Narayanan

Published: 13 February, 2024 | Volume 8 - Issue 1 | Pages: 001-002

Herpes zoster ophthalmicus, commonly referred to as shingles, manifests as a painful skin rash affecting one or more dermatome distributions of the trigeminal nerve, which supplies sensory innervation to the eye and its surrounding structures. Acyclovir stands as the primary pharmacological intervention for the treatment of this condition. However, its administration is associated with a notable risk of adverse effects, with acute kidney injury being the most prevalent. Herein, we present a case report involving a 59-year-old female patient who developed acute kidney injury after the prescription of Acyclovir for the management of herpes zoster ophthalmicus. This case underscores the importance of vigilance regarding potential renal complications associated with Acyclovir therapy, particularly in susceptible patient populations.

Read Full Article HTML DOI: 10.29328/journal.apps.1001048 Cite this Article Read Full Article PDF

Keywords:

Acyclovir; Acute kidney injury; Serum creatinine

References

  1. Acyclovir (Oral Route, Intravenous Route) Description and Brand Names - Mayo Clinic. (n.d.). Www.mayoclinic.org. https://www.mayoclinic.org/drugssupplements/acyclovir-oral-route-intravenous-route/description/drg-20068393#:~:text=Acyclovir%20is%20used%20to%20treat
  2. Zachary KC. Acyclovir: An overview, UpToDate; 2022, https://www.uptodate.com/contents/acyclovir-an-overview
  3. Yildiz C, Ozsurekci Y, Gucer S, Cengiz AB, Topaloglu R. Acute kidney injury due to acyclovir. CEN Case Rep. 2013 May;2(1):38-40. doi: 10.1007/s13730-012-0035-0. Epub 2012 Oct 1. PMID: 28509218; PMCID: PMC5411519.
  4. Abuhelwa Z, Beran A, Venkataramany BS, Hinch BT, Assaly R. Concurrent Nephrotoxicity and Neurotoxicity Induced by Oral Valacyclovir in a Patient With Previously Normal Kidney Function. Cureus. 2022 Mar 31;14(3):e23693. doi: 10.7759/cureus.23693. PMID: 35509998; PMCID: PMC9060728.

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