Research Article
Published: 29 March, 2024 | Volume 8 - Issue 1 | Pages: 021-023
In the biopharmaceutical production field, the purification process is a crucial step in order to obtain Drugs with an impurity profile according to the regulatory agency requirement.
The aim of this work is to verify some relevant and recent literature and after analysis to submit to the researcher new Solutions in order to improve global safety and the toxicological profile: Submit a project related to the continuous testing of the purified materials using Raman spectroscopy – with pre-treatment of the sample: using solvents.
Nanolipis Payload of Biopharmaceutical is not efficiently detected by direct Raman spectroscopy allowed by the regulatory agency for PAT process analytical technology.
Read Full Article HTML DOI: 10.29328/journal.apps.1001052 Cite this Article Read Full Article PDF
mRNA; Purifications; Chromatography; Separations; Columns; Resins; Monoliths; Activated carbon; Raman spectroscopy; Pre-treatment of sample; Continuous testing systems
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